What is this drug used for?
– It is used to treat a skin problem called dermatitis herpetiformis.
– It is used to treat leprosy.
– It may be given to you for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
– Abdominal pain
– Trouble sleeping
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
– Liver problems dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin
– Kidney problems like not able to pass urine, blood in your urine, change in amount of urine passed, or weight gain
– Lupus like rash on the cheeks or other body parts, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs
– Pancreatitis like severe abdominal pain, severe back pain, severe nausea, or vomiting
– Severe loss of strength and energy
– Burning or numbness feeling
– Muscle weakness
– Difficulty moving
– Blurred vision
– Noise or ringing in the ears
– Mood changes
– Pale skin
– Fast heartbeat
– Purple spots or redness of skin
– Toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes.
– Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Dapsone may be confused with Diprosone
Storage and Stability
Store at 20?C to 25?C (68?F to 76?F). Protect from light.
Central nervous system: Fever, headache, insomnia, psychosis (oral/topical), vertigo
Dermatologic: Bullous and exfoliative dermatitis, erythema nodosum, exfoliative dermatitis, morbilliform and scarlatiniform reactions, phototoxicity, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria
Endocrine & metabolic: Hypoalbuminemia (without proteinuria), male infertility
Gastrointestinal: Abdominal pain, nausea, pancreatitis, vomiting
Hematologic: Agranulocytosis, anemia, leukopenia, pure red cell aplasia (case report); hemolysis (dose related; seen in patients with and without G6PD deficiency), hemoglobin decrease (1-2 g/dL), reticulocyte increase, methemoglobinemia, red cell life span shortened
Hepatic: Cholestatic jaundice, hepatitis
Neuromuscular & skeletal: Lower motor neuron toxicity (prolonged therapy), lupus-like syndrome, peripheral neuropathy (rare, nonleprosy patients)
Ophthalmic: Blurred vision
Renal: Albuminuria, nephrotic syndrome, renal papillary necrosis
Respiratory: Interstitial pneumonitis, pulmonary eosinophilia
Miscellaneous: Infectious mononucleosis-like syndrome (rash, fever, lymphadenopathy, hepatic dysfunction)