Colchicine Information
Pronunciation
KOL chi seen
What is this drug used for?
– It is used to treat gout attacks.
– It is used to prevent gout attacks.
– It is used to treat familial Mediterranean fever.
– It may be given to you for other reasons. Talk with the doctor.
Frequently reported side effects of this drug
– Diarrhea
– Nausea
– Vomiting
– Abdominal pain
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
– Infection
– Burning or numbness feeling
– Severe loss of strength and energy
– Bruising
– Bleeding
– Pale skin
– Muscle pain
– Muscle weakness
– Unable to pass urine
– Change in amount of urine passed
– Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
Colchicine may be confused with Cortrosyn
Product Availability
Gloperba (0.6 mg/5 mL oral solution): FDA approved January 2019; availability anticipated mid-2019. Information pertaining to this product within the monograph is pending revision. Consult the prescribing information for additional information.
Storage and Stability
Store at 20?C to 25?C (68?F to 77?F). Protect from light and moisture.
Adverse Reactions
Central nervous system: Fatigue, headache
Endocrine & metabolic: Gout
Gastrointestinal: Abdominal cramps, abdominal pain, diarrhea, gastrointestinal disease, nausea, vomiting
Respiratory: Pharyngolaryngeal pain
Rare but important or life-threatening: Alopecia, bone marrow depression, dermatitis, disseminated intravascular coagulation, dysgeusia (Syed 2016), hepatotoxicity, hypersensitivity reaction, increased creatine phosphokinase in blood specimen, lactose intolerance, myalgia, myasthenia, oligospermia, nonthrombocytopenic purpura, rhabdomyolysis, toxic neuromuscular disease
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